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Analiza Inc log-d value
Log D Value, supplied by Analiza Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/log-d+value/log+d+value/us09789199-777-12-36
Average 90 stars, based on 1 article reviews
log-d value - by Bioz Stars, 2026-09
90/100 stars

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Article Title: An orally delivered small-molecule formulation with antiangiogenic and anticancer activity.
Article Snippet: In order to predict the intestinal absorption of TNP-470, we measured its log-D value which is a parameter of hydrophobicity determined by the ratio of drug concentration in octanol to that in water at 25 1C (Analiza).

Article Title: MetAP-2 inhibitor polymersomes for therapeutic administration
Article Snippet: In order to predict the intestinal absorption of TNP-470, we measured its Log-D value which is a parameter of hydrophobicity determined by the ratio of drug concentration in octanol to that in water at 25° C. (Analiza, Cleveland Ohio).

Article Title: An orally delivered small-molecule formulation with antiangiogenic and anticancer activity
Article Snippet: In order to predict the intestinal absorption of TNP-470, we measured its log-D value which is a parameter of hydrophobicity determined by the ratio of drug concentration in octanol to that in water at 25 °C (Analiza).



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DMPK and Safety Profile of Compounds 6 , 12 , 13 , 14 , 22 , 23 , 27 , 36 , 40 , 47 and BM635

Journal: ACS Medicinal Chemistry Letters

Article Title: Novel Pyrazole-Containing Compounds Active against Mycobacterium tuberculosis

doi: 10.1021/acsmedchemlett.9b00204

Figure Lengend Snippet: DMPK and Safety Profile of Compounds 6 , 12 , 13 , 14 , 22 , 23 , 27 , 36 , 40 , 47 and BM635

Article Snippet: Moreover, compounds with MICs < 1 μM were evaluated to determine the drug metabolism and pharmacokinetics (DMPK) profile (Chrom log D pH7.4 values, artificial membrane permeability, percentage of binding to human serum albumin (HSA), kinetic solubility, solubility in the biorelevant medium to simulate fasted states in vivo (FaSSIF), and human ether-a-go-go-related gene (hERG)) binding, and those providing the best profile were selected to determine their efficacy in vivo.

Techniques: Membrane, Permeability